Over the last few years, peptide therapy has been widely viewed as an effective treatment that can handle various medical conditions. What are peptides, you ask? Well, peptides are short-chain amino acids (usually made up of 2 to 52 amino acid chains) that naturally reside inside the human body. They’re typically used as building blocks for proteins and send messages instructing cells and molecules to perform their specific tasks inside the body. By using synthetically configured versions of these short amino acid chains, peptide therapy works as a viable regenerative treatment that increases the effectiveness of this process and enhances a particular cell’s ability to perform its assigned function. As such, peptide therapy can be used to improve the immune system, enhance cognitive function, and even stimulate weight loss.
Recently the Tesamorelin peptide has grown increasingly popular for its ability to reduce body fat. FDA-approved in 2010 as a weight loss medication for HIV patients suffering from lipodystrophy, a condition that causes an accumulation of fat in the abdominal area, Tesamorelin has been viewed as an optimal weight loss treatment for non-HIV patients striving to manage their weight.
But what is Tesamorelin? And how does it work? In this article, we’ll discuss how Tesamorelin can help with weight management and go over the essential details you’ll need to know about the medication before using Tesamorelin as a weight loss treatment.
What Is Tesamorelin?
Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) peptide. Unlike other GHRH analogs and even the natural form of the hormone found in the brain, Tesamorelin contains the entire GHRH amino acid sequence and a trans-3 hexenoic group to protect it from enzymatic degradation, which makes it more stable and extends its half-life.
What Does The Peptide Tesamorelin Do?
Once Tesamorelin is inside the human body, the peptide binds to GHRH receptors to stimulate the pituitary gland into releasing growth hormone at a rate similar to the body’s naturally occurring GHRH traveling through the bloodstream. Once more growth hormone is released, it boosts metabolism and improves muscle growth, which helps to burn more calories and decrease body fat. The peptide can also help to increase insulin growth factor (IGF-1), which can help to lower glucose levels and further stimulate weight loss. As a result, Tesamorelin can help reduce visceral adipose tissue, leading to improved belly appearance, size, and waist circumference.
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What Are the Benefits of Tesamorelin?
Because Tesamorelin can help stimulate human growth hormone production, patients can experience several benefits from using Tesamorelin for fat loss, such as:
- Significant IGF-1 increase
- Reduced visceral fat
- Increased muscle mass
- Reduced liver fat
- Improved cardiovascular health
- Reduced LDL cholesterol
- Improved cognitive function
- Accelerated recovery time after workouts
Tesamorelin can also produce notable improvements in cognitive function for healthy adults and seniors with early signs of dementia. The peptide can also improve lipid profile and cardiovascular health by decreasing the intima-media thickness of the carotid arteries, which can help prevent atherosclerotic vascular disease.
Who Is a Good Candidate for This Medicine?
Anyone striving to manage their body’s physical composition, boost their immune system, and improve their overall health can benefit from Tesamorelin.
What Should You Know Before Taking Tesamorelin for Weight Loss?
Unfortunately, like all prescription medications, Tesamorelin may not be a viable treatment for everyone. Your physician may suggest that you avoid taking Tesamorelin if you have pre-existing conditions such as:
- Pituitary gland disorder
- Allergies to certain ingredients such as Mannitol
- Head pressure
- Lung complications
- Kidney disease
- Diabetes
- Adrenal gland disorder
- Epilepsy
- Heart disease
- High blood pressure
Potential patients with a history of cancer or benign or malignant tumors should also avoid using Tesamorelin. Inform your doctor if you’ve previously had radiation treatment or open heart surgery before taking Tesamorelin. Women who become pregnant during Tesamorelin treatment should discontinue the medication immediately after confirmation to avoid serious complications since using the medication may harm the unborn fetus and cause congenital disabilities.
How To Take
Tesamorelin is typically sold in powder form and needs to be mixed with water before it can be used as an injection. Before mixing the treatment, store the needles, syringes, and the box of sterile water used for injection at room temperature. Because Tesamorelin is a highly fragile peptide, you will need to mix it gently in sterilized water for optimal dilution. Once it has been reconstituted into a liquid form, you will need to store the mixture in the refrigerator for the recommended duration of treatment. Always store your Tesamorelin out of reach of children or any pets you may have. You will also need to keep the box of medication in a place away from direct light. You should always check the medication to make sure that it hasn’t changed colors or has particles in it. If that occurs, discard the medication and call your physician for a new prescription.
Tesamorelin injections are typically given subcutaneously under the skin of your stomach once a day. When picking the injection site, choose a place below the belly button and avoid any area that may have scar tissue, bruises, reddening, and irritation. Make sure to clean the injection site with rubbing alcohol before injecting each dose. You should also rotate the injection site each time to avoid any redness or irritation after the injection.
Once you’re done with the injection, throw away any used needles and syringes in a hard closed container so the needles can’t poke through. This container should also be kept out of the reach of children and pets.
What Happens if I Take Too Much Tesamorelin?
Unfortunately, since every patient’s reaction to Tesamorelin may be different, there’s no definitive information available about what happens if you overdose. However, if you think you’re experiencing an overdose or abnormal side effects, call a healthcare provider and seek immediate medical attention. If the side effects persist and become more severe, call 911 immediately.
What Should I Do if I Missed a Dose of Tesamorelin?
If you miss your regular dose of Tesamorelin, take it as soon as you can remember. However, if you know your missed dose will be closer to the timeframe for your next Tesamorelin dosage, skip the missed dose and resume your regular dosing schedule to avoid overdosing.
What Are the Side Effects?
Like most prescription medications, Tesamorelin may have some unwanted and, sometimes, serious side effects. Most minor side effects may dissipate during treatment as your body adjusts to the medication. In either case, contact your physician if you experience the following:
Common Side Effects
- Depression
- Pain or numbness
- Muscle pain
- Vomiting
- Night sweats
- Joint inflammation
- Swelling and fluid retention
- Redness or bruising at the injection site
Severe Side Effects
- Rash
- Hives
- Shortness of breath
- Fast heartbeat
- Swelling in the face or throat
- Fainting
Although it’s rare for these more severe side effects to occur, you should seek medical attention immediately if you begin experiencing these issues.
Long-Term Side Effects
Long-term usage of Tesamorelin can also lead to long-term side effects such as:
- Increased risk for cancer
- Carpal tunnel syndrome
- Diabetes
- Increased risk of death in critically ill people
Make sure to disclose your medical history and pre-existing medical conditions with your physician before using Tesamorelin. They can expertly weigh the benefits and risks of Tesamorelin on your health and determine if the medication will be a safe long-term treatment option for you.
What Other Medications Interact With Tesamorelin?
There are over 46 medications that may interact with Tesamorelin and compromise the drug’s effectiveness, including:
- Simvastatin
- Ritonavir
- Prednisone
- Cortisone
- Cyclosporine
These are only a few to name, so make sure to discuss with your doctor any herbs, plant-based medicines, vitamins, prescription and non-prescription medications that you currently or plan to take before starting Tesamorelin treatment. This can help your healthcare provider determine if Tesamorelin will work with your medications, prepare for possible issues, and adjust your treatment as needed to help you avoid adverse interactions.
How Long Does It Take To See Results From Tesamorelin?
The amount of time it will take to see results after using Tesamorelin can vary depending on a number of factors, including the individual’s physical condition, the dosage used, and the length of treatment, so any results you achieve will depend on how your body responds to the medicine. However, in clinical trials, patients who used Tesamorelin for weight loss saw a significant decrease in visceral fat after 26 weeks of treatment.
At the Renew Vitality Clinic, we specialize in helping patients utilize peptide therapy to achieve weight loss. Our experienced staff can provide safe and effective peptide treatments, such as Tesamorelin injections, to help you reduce belly fat, improve cognitive function, and improve your overall health. Contact us at 1-800-785-3945 and schedule an appointment at any one of our hormone replacement clinics in the United States to learn more about what Tesamorelin can do for you.
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