Bremelanotide – PT-141
What is Bremelanotide?
Bremelanotide, also known as PT-141, is a melanocortin receptor agonist developed to treat sexual dysfunction by acting directly on the brain’s arousal centers. Unlike medications that affect blood flow, such as Viagra or Cialis, Bremelanotide works through neural pathways to enhance sexual desire and responsiveness. It is typically prescribed for low sexual desire in women and is also used in men for erectile dysfunction and libido support.
How Bremelanotide Works
Think of Bremelanotide as a “neurochemical ignition switch” for sexual arousal. It activates melanocortin-4 receptors in the central nervous system, triggering pathways associated with motivation, attraction, and arousal. This allows it to enhance both desire and physical readiness for intimacy, regardless of blood flow issues.
Potential Benefits of Bremelanotide Therapy
When used under provider supervision, patients may experience the following potential and anecdotal benefits:
In Women (Especially with Low Desire or HSDD): Increased interest in intimacy and more frequent initiation; a stronger sense of mental and emotional arousal; improved satisfaction with sex and overall sexual well-being; greater sensitivity and physical responsiveness during intercourse; more spontaneous desire rather than relying on external cues or foreplay. Patients have reported feeling more “in tune” with their partners and regaining a sense of confidence in their sexuality.
In Men (Especially with Erectile Dysfunction or Low Libido): Enhanced erectile response—especially when combined with PDE5 inhibitors (e.g., sildenafil); faster onset of arousal and fewer psychological blocks around performance; improved morning erections and libido on non-treatment days; more reliable sexual performance during stress or fatigue; a renewed interest in sex that feels more “natural” than forced. Men often describe feeling “like themselves again”—more driven, focused, and present during intimate moments.
What to Expect
Bremelanotide is typically administered as a subcutaneous injection in the abdomen or thigh, taken 30 to 60 minutes before sexual activity. For women, it’s generally used as-needed rather than on a daily schedule. In men, it can be used either alone or in combination with medications like sildenafil or tadalafil for compounded benefit. Some individuals notice immediate effects; others may respond more gradually after a few uses.
Is Bremelanotide Right for you?
If you experience low sexual desire, arousal issues, or dissatisfaction with your intimate life, Bremelanotide may offer a new pathway forward. It’s ideal for premenopausal women with hypoactive sexual desire disorder (HSDD), men who don’t respond fully to PDE5 inhibitors alone, individuals seeking to reconnect with their libido after hormonal changes, stress, or aging, and couples exploring new ways to revitalize intimacy.
Important to Note
Side effects may include nausea, flushing, headache, temporary increase in blood pressure, and injection site reactions. Should not be used more than once in 24 hours or more than 8 times per month. Not recommended in individuals with uncontrolled hypertension or certain cardiovascular conditions without physician approval. Bremelanotide is not a hormone and does not affect estrogen or testosterone levels directly.
How to Use Bremelanotide
• Reconstitute lyophilized powder with bacteriostatic water according to pharmacy instructions
• Draw the prescribed dose with an insulin syringe (0.5 mL or 1 mL)
• Inject subcutaneously in the abdomen or intramuscularly, as directed
• Store the reconstituted vial in the refrigerator
• Rotate injection sites to minimize irritation
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FAQ
How is Bremelanotide Administered?
Sermorelin is typically administered by injection subcutaneously typically in the stomach or thighs. Your Patient Coordinator will guide you to ensure proper preparation and administration.
Is Bremelanotide Safe?
Bremelanotide is consider safe by healthcare professionals while in use under medical supervision. For patients at risk of cardiovascular disease, Bremelanotide should be used with caution.
Who can benefit from Bremelanotide?
Bremelanotide may benefit women with low desire or HSDD, and men with erectile dysfunction or low libido. It’s important to consult with a Renew Vitality medical expert.
Ready to Rediscover Your Desire with Renew Vitality?
If you’ve been feeling disconnected from your libido or struggling with intimacy, Bremelanotide could be a science-backed option worth exploring. Speak with your Renew Vitality provider to see if it’s the right fit for your sexual wellness goals.
Our personalized wellness programs are designed to help renew your health and wellness. Contact us today to unlock your full potential.
