How Testosterone Works
Testosterone production starts at just 8 weeks of gestation. To put that in perspective, from the time you were the size of a bean, and before the formation of your genitals, you were producing T. It’s a common misconception that T’s functions are limited to its pubescent effects–deepening our voice, filling out our muscles, making us taller, and allowing us the ability to procreate.
T production doesn’t end once we reach adulthood, and for good reason. Testosterone is crucial for very basic physiological functions including red blood cell production, fat metabolism, protein synthesis, bone maintenance, and reproduction.
T is created in two places in the male body, the testes, and the adrenal cortex. Leydig cells in the testes do the lion’s share of the work, accounting for upwards of 95% of circulating T. The adrenal glands produce a small number of weak androgens that can be converted to T, like androstenedione and DHT–the hormone responsible for male-patterned balding.
Testosterone synthesis is a lengthy process involving many hormones, precursors, enzymatic reactions to transform cholesterol into the steroid hormone that we’re familiar with. Since testosterone is derived from cholesterol and thus fat-soluble, it transitions easily from the testes into the bloodstream, by slipping through cell membranes and moving from areas of high concentration to areas of lower concentration and into the blood vessels.
T asserts it’s physiological effects by attaching to androgen receptors much like a lock and a key. Androgen receptors are found all throughout the body and are highly concentrated in our stomach lining, brain, muscles, kidneys, and liver and fat.
What Is a Normal Testosterone Range?
For decades, scientists and doctors have debated what classifies as a normal testosterone level. Quantifying a normal testosterone range is difficult since, even in the healthiest of men, levels change from year to year T levels are reflective of our general health.
According to an article written by Charles Patrick Davis, MD, Ph.D., “the normal range in males is about 270-1070 ng/dL with an average level of 679 ng/dL.” Dr, Davis goes on to say that “some researchers suggest that the healthiest men have testosterone levels between 400-600 ng/dL.”
A study of almost 10,000 men, aimed at quantifying normal T levels found the “normal range for testosterone in a non-obese population of European and American Men, 19-39 years, is 264-916 ng/dL.” Still, some scientists argue that anything below 300 ng/dl is far too low for even men well into advanced age.
Obese men, those with chronic illnesses, or who have chemical dependencies (particularly to opiates, alcohol, or tobacco) often have significantly lower levels and a higher risk for developing low T.0
Symptoms of Low T
- Decrease red blood cell counts
- Decreased libido
- Difficulty falling or staying asleep
- Dry skin and/or hair
- Feelings of sadness or anxiety
- Less spontaneous erections
- Loss of body and beard hair
- Low hemoglobin levels
- Night sweats and/or hot flashes
- Persistent migraines
- Trouble concentrating
- Weak bones and muscles
A quick web search will reveal hundreds of symptoms of low T. Above are some of the most common side effects of a testosterone imbalance, though it’s important to remember that rarely do men have all the symptoms and sometimes display no symptoms at all. 0
Finding Testosterone Replacement Therapy in Pearl River
If you’re from the small township of Pearl River, you’re probably thinking you’ll have quite a drive to receive decent healthcare, but the local options might surprise you. Pearl River is home to one of the newest Renew Vitality facilities on the east coast. Renew Vitality is a chain of America’s most trusted anti-aging and HRT clinics, with thousands of satisfied patients all over the country. Our offices are staffed with some of the fields most distinguished physicians.
The Pearl River office is located at 150 South Pearl Street beside the car wash and is open weekdays from 8 am to 6 pm, excluding national holidays.
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